Trichosanthes japonica agglutinin I and II (TJA-I and TJA-II)
• Two variants
• Affinity for lactose
• Ultrapure quality
• Diagnosis of colon cancer (TJA-I)
• Anti-H agglutinin (TJA-II)
TJA-I is along with its isolectin TJA-II isolated from the root tubers of Japanese gourd. They are highly purified and one purification step involves bio specific affinity chromatography to ensure highest possible binding affinity. They both have affinity for lactose but while TJA-II favours fucose a1->2 lactose TJA-I favours acidic groups coupled to N-Acetyl-D-lactosamine in 1,4 position.
Storage and Stability
Stable for at least 3 years from production date when stored below -20 ̊C. May be shipped at ambient temperature. After reconstitution in PBS pH 7.4, the solution may be stored frozen in working aliquots for up to 12 months. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.
(1) Liener I. E., Sharon N., Goldstein I. J., (1986) The Lectins – Properties, Functions and Applications in Biology and Medicine.