Expertise and Capabilities at your service

Medicago’s experienced and highly-qualified staff of product development and manufacturing scientists is on hand to provide our partners with a wide range of competences and capabilities. We are committed to putting your needs first. Our Project Leader will manage the entire process to ensure the success of your project.

Our areas of expertise:

• Process engineering                  
• Immunology
• Organic chemistry                  
• Parasitology
• Analytical chemistry                  
• Microbiology
• Biochemistry                  
• Cell biology
• Molecular biology

Our capabilities include the following operations:

Chemical synthesis

A wide range of organic preparative services fit the needs of our diverse clientele. Our experienced staff share their expertise in the synthesis of non-commercial
compounds by:

We manufacture speciality chemicals, drug intermediates and analytical bio-reagents in quantities from milligrams to kilograms with high standards of quality, safety and reproducibility.

Fermentation

We have the capability to grow bacteria and yeast under stringently controlled conditions using state-of-the-art fermentation systems. Our fermentation service provides clients with a wide range of growth conditions plus high reproducibility for their products. Vector design and recombinant protein purification services are also available.

Fully-automated bioreactors Highly customizable Optimization of expression and growth conditions Validated clean-room environment Process development on request Downstream processing and large scale separation

Downstream Processing and Separation

Our services in this area assist clients from early research and development to pilot studies, manufacture and delivery of the final product. Medicago can engineer a process and provide cell or protein extracts, fractions or pure products specific to your requirements. Our extensive facilities include modern, large-scale instrumentation and systems. We use integrated technologies and a wide variety of separation techniques, e.g. industrial-scale liquid chromatography, to provide protein fractions or pure proteins.

Fully cGMP complaint State-of-the-art equipment Industrial-scale separation equipment Process engineering on request Ultrafiltration capability Continuous centrifuges

Aseptic Filling

Medicago offers both liquid and powder filling under aseptic conditions from small to production scale, capacity from 0,6 ml to 50 ml per vial. Our dedicated clean area for formulation/preparation and filling machine, is optimized to handle monoclonals, recombinant proteins, RNA, vaccines, enzymes, lectins, saponins and other bioreagents. The aseptic filling area has direct access to our large scale freeze drying unit.

Fully cGMP complaint Controlled clean environment Fully-automated lines Wide range of vial sizes Automated product labeling Formulation and process development

Freeze-drying

Medicago’s contract freeze-drying capability is one of the largest in Northern Europe. Our state-of-the-art freeze dryers accommodate up to 120 kilos of material or 25,000 vials. We have the capacity to satisfy industrial customer requests for both bulk and vial freeze-drying from pilot to production scale. Furthermore, we offer aseptic-filling freeze-drying that meets most customer needs in this area.

Development of freeze-drying processes Fully cGMP compliant Automated cleaning and sterilization of equipment (SIP&CIP) Fully-automated processes Aseptic freeze-drying From one milligram to 120 kilograms